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New scientific research confirms the beneficial effect of MASQUELIER’s® Original OPCs on the viability and integrity of endothelial cells when exposed to oxidative stress. The food supplement protects endothelial cells by increasing the cells’ capacity to survive oxidative stress. In addition, endothelial cells are protected against oxidative stress in the presence of MASQUELIER’s® Original OPCs. This is how MASQUELIER’s® Original OPCs protects endothelial cells from oxidative stress by scavenging free radicals inside as well as outside the cells.
The MASQUELIER’s® product comprises single and slightly condensed forms of flavanols, as verified by HPLC. The ex vivo study, which is ongoing at the University of Utrecht (The Netherlands), investigates the ability of MASQUELIER’s® Original OPCs to protect vascular endothelial cells from oxidative damage. The first results of the research project were presented at the XIIth Annual Meeting on Oxidants and Antioxidants in Biology, held last week in Santa Barbara by the Oxygen Club of California (OCC) by International Nutrition Company’s (INC) Dr. Sujata Bapat. The compound, sold by INC as a food supplement under the ANTHOGENOL® trademark, has become well known for its numerous vascular benefits. The vast body of research that underpins ANTHOGENOL’s® active principle has now been enriched with the scientific certainty that the product specifically protects endothelial cells under oxidative stress. Endothelial cells not only form the dynamic inner lining of the entire vascular system. They play a key role in capillary function, because capillaries consist of nothing other than endothelial cells. This is why, at the capillary level, endothelial cells determine permeability and exchange of micro- and macromolecules between blood and tissues and vice versa.
Free radicals are involved in numerous seemingly unrelated conditions such as inflammation, atherosclerosis and premature aging. Radical damage to the endothelial cells that line vasculature results in endothelial dysfunction, which in turn plays an important role in the onset and progression of vascular disease. As INC’s Dr. Sujata Bapat explains: "We now have conclusive evidence that ANTHOGENOL preserves the viability and integrity of vascular endothelial cells. The research shows that ANTHOGENOL® supplementation resulted in a >85% protection of endothelial cells from oxidative stress. ANTHOGENOL® provides antioxidant support to the vascular endothelial cells whether present intracellularly and extracellularly." INC’s chairman, Bert Schwitters, adds: "This is another pearl in the string of scientific data that demonstrates the broad nutritional support provided by our MASQUELIER’s® food supplements. It confirms the links between the product’s antioxidant effects and its well established effects on vascular health. As the research continues, our ever improving understanding of this unique product will lead to more and more solid health claims in the field of vascular health."
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